Pioneering Steps in Xenotransplantation: Pig Kidney Trials in Humans
The first clinical trial to assess pig kidney transplantation in humans has commenced. United Therapeutics reported a successful initial transplant at NYU Langone Health. As efforts in xenotransplantation progress, additional trials are underway, eyeing a solution to the organ shortage problem.
- Country:
- United States
In a groundbreaking move, a clinical trial to evaluate the viability of pig kidney transplants in humans has begun. United Therapeutics, known for producing gene-edited pig kidneys, made headlines with the successful execution of an initial transplant at NYU Langone Health, setting a new precedent in medical science.
This development marks a significant step forward in the search for animal-to-human transplants or xenotransplantation. As the trial progresses, more centers are expected to partake, potentially offering a revolutionary solution to the organ shortage crisis that currently sees over 100,000 people on the US transplant list.
The trials involve pig kidneys with 10 gene edits designed to reduce rejection and enhance compatibility. Previous efforts saw varying outcomes, but the current trial aims to learn from past experiences to improve future success rates. This pioneering approach could dramatically transform transplant medicine.
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