Brain's Waste Management During Sleep Deprivation: The Hidden Cost of Attention Lapses

A study investigates how sleep deprivation affects attention due to the brain's attempt at waste cleansing during wakefulness. Researchers found that cerebrospinal fluid cleansing intrudes into wakeful periods, resulting in attentional failures. The study suggests a link between brain waste clearance and cognitive function, crucial for preventing dementia.


Devdiscourse News Desk | New Delhi | Updated: 29-10-2025 17:06 IST | Created: 29-10-2025 17:06 IST
Brain's Waste Management During Sleep Deprivation: The Hidden Cost of Attention Lapses
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A groundbreaking study has highlighted a hidden cost of sleep deprivation: attention lapses linked to the brain's waste-cleansing process. Researchers discovered that cerebrospinal fluid, crucial for brain health, intrudes into waking hours during lack of sleep, disrupting attentional capabilities.

Conducted by MIT scientists, the research tested 26 participants on attention tasks after a night without sleep. The findings, published in Nature Neuroscience, showed how sleep deprivation impairs brain function, suggesting waste clearance might compensate at attention's expense. Lead researcher Laura Lewis underscored the physiological changes observed.

The study points to a brain-body connection in managing sleep-deprivation's effects. Lapses are marked by reduced breathing, pupil constriction, and fluid dynamics, indicating the brain's struggle to maintain cognitive performance. This research underscores the importance of sleep in preventing cognitive decline and related disorders like dementia.

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