Breakthrough in Vaccine Development Against Epstein-Barr Virus Linked to Multiple Serious Illnesses

Researchers are progressing towards a vaccine against Epstein-Barr virus (EBV), which affects 95% of the global population and is linked to multiple serious diseases. Utilizing human antibody genes in mice, scientists developed antibodies that showed partial to full prevention of the virus in preclinical trials, signaling hope for high-risk patients.


Devdiscourse News Desk | Updated: 25-02-2026 17:30 IST | Created: 25-02-2026 17:30 IST
Breakthrough in Vaccine Development Against Epstein-Barr Virus Linked to Multiple Serious Illnesses
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In a significant stride in medical research, scientists are closing in on a potential vaccine for the Epstein-Barr virus (EBV), a pervasive virus linked with infectious mononucleosis, multiple sclerosis, and certain cancers. Researchers successfully generated antibodies in mice, indicating promising pathways to prevent the virus's infection and activation.

Using mice engineered to carry human antibody genes, scientists developed ten monoclonal antibodies targeting two critical proteins on the virus surface. One antibody effectively prevented EBV infection in mice, with partial success reported from another. Researchers believe this marks a pivotal moment for high-risk groups vulnerable to EBV-associated complications.

EBV poses severe risks, particularly for immunosuppressed individuals such as transplant recipients. Innovators from Fred Hutch Cancer Center emphasize the need for a vaccine, while another study raises concerns about the presence of microplastics in prostate cancer tissues, potentially triggering further health implications.

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